Synthetic, plasma-free, transfusible storage medium for red bloo

Details Synthetic, plasma-free, transfusible storage medium for red bloo Synthetic, plasma-free, transfusible storage medium for red bloo

1993-09-28

1996-01-30

Naff, David M.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

424533, 424529, 424532, A61K 3518, A61K 3514, A01N 102

Patent

active

054879710

ABSTRACT:
The invention is a sterile, plasma-free storage medium for blood components including red blood cells and for platelets processed separately or together. The red cell storage medium includes adenine and a physiologically compatible, aqueous electrolyte solution. In one liter of this electrolyte solution there is between about 3.0 grams and about 25.0 grams of dextrose, between about 3.0 grams and about 6.0 grams of sodium citrate, and between about 2.0 grams and about 4.2 grams of sodium bicarbonate. The red cell storage medium is isotonic and has a pH in a range of between about 6.8 and about 7.4. The red cell storage medium is capable of storing and preserving red cells for at least 49 days.

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