Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1992-10-09
1996-03-19
Wax, Robert A.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
536 2371, 935 10, 935 35, C12N 1532, C12N 1582
Patent
active
055003656
ABSTRACT:
A method for modifying structural gene sequences to enhance the expression of the protein product is disclosed. Also disclosed are novel structural genes which encode insecticidal proteins of B.t.k. HD-1, B.t.k. HD-73, B.t. tenebrionis, B.t. entomocidus, 2 protein of B.t.k. HD-1, and the coat protein of potato leaf roll virus.
REFERENCES:
patent: 4448885 (1984-05-01), Schnepf et al.
patent: 4771131 (1988-09-01), Herrnstadt et al.
patent: 5082767 (1992-01-01), Hatfield
patent: 5380831 (1995-01-01), Adang et al.
Honee et al., Nucleotide Sequence of Crystal protein Gene Isolated from B. thuringinesis Subspecies, entomocidus 60.5 Coding for a Toxin Highly Active Against Spodoptera Species, Nuc. A. R., (1988) vol. 16, No. 13, p. 6240.
Kozak, M. Influences of mRNA Secondary Structure on Initiation by Eukaryotic Ribosomes, Biochemistry, Proc. Natl.Acad.Sci.USA, (1986) vol. 83, pp. 2850-2854.
Dean et al., mRNA Transcripts of Several Plant Genes are Polyadenylated At Multiple Sites in Vivo, Nuc.A.R., (1986) vol. 14, No. 5, pp. 2229-2240.
Shaw and Kamen A Conserved AU Sequence from the 3' Untranslated Region of GM-CSF and mRNA Mediates Selective mRNA Degradation, Cell, (1986), vol. 46, pp. 659-667.
Hoekema et al., Codon Replacement in the PGK1 Gene of Saccharomyces cerevisiae: Experimental Approach to Study the Role of Biased Codon Usage in Gene Expression, Mol. & Cell. Biol., (1987) vol. 7, No. 6, pp. 2914-2924.
Donovan et al. Amino Acid Sequence and Entomocidal Activity of the P2 Crystal Protein, J. of Biol. Chem., (1988) vol. 263 No. 1, pp. 561-567.
Vaeck et al., Transgenic Plants Protected from Insect Attack Nature (1987) vol. 328, pp. 33-37.
Wiebauer et al., Nuclear Pre-mRNA Processing in Plants: Distinct Modes of 3'-Splice-Site Selection in Plants and Animals, Mol. & Cell.Biol., (1988) vol. 8, No. 5, pp. 2042-2051.
Dalbadie-McFarland et al., Oligonucleotide-Directed Mutagenesis as a General and Powerful Method for Studies of Protein Function, Biochemistry, Proc.Natl.Acad.Sci. USA) (1982) vol. 79, pp. 6409-6413.
Reines et al., Identification of Intrinsic Termination Sites in Vitro for RNA Polymerase II Within Eukaryotic Gene Sequences, J.Mol.Biol. (1987) vol. 196, pp. 299-312.
Adang et al., Expression of a Bacillus thuringiensis Insecticidal Crystal Protein Gene in Tobacco Plants UCLA Symp.Mol.Cell.Biol. (1987) vol. 48, pp. 345-353.
Barton et al., Bacillus thuringiensis 8-Endotoxin Expressed in Transgenic Nicotiana tabacum Provides Resistance to Lepidopteran Insects, Plant Physiol., (1987) vol. 85, pp. 1103-1109.
Murray et al., Codon Usage in Plant Genes, Nuc.A.R., (1989) vol. 17, No. 2, pp. 477-498.
Smith et al., Molecular Cloning of Potato Leaf Roll Virus Complementary DNA, Biol. Abstr. Phytopathology, (1989) vol. 87(2) AB. 9696.
Wickens et al., Cleavage and Polyadenylation of SV40 Late Pre-mRNAs In Vitro, Abstract presented at meeting on RNA Processing, May 13-17, 1987, Cold Spring Harbor, p. 9.
Proudfoot et al., Termination of Transcription and 3' end Processing in Eukaryotic Genes Transcribed by RNA Polymerase II: The Signals Involved and their Role in Gene Regulation, Abstract presented at meeting on RNA Processing May 13-17, 1987, Cold Spring Harbor, p. 17.
Pandey and Marzluff, Processing and Stability of Transcripts from Chimeric Histone-Globin Genes, Abstract presented at meeting on RNA Processing May 13-17, 1987, Cold Spring Harbor, p. 133.
Tsurushita and Korn, Regulation of Differential Processing of Mouse Immunogloublin Mu Heavy-Chain mRNA, Abstract presented at meeting on RNA Processing May 13-17, 1987, Cold Spring Harbor, p. 215.
Shaw and Kamen, Characterization of AU Sequences Functioning as mRNA Destabilizers, Abstract presented at meeting on RNA Processing, May 13-17, 1987, Cold Spring Harbor, p. 220.
Adami and Nevins, Adenovirus mRNA Processing--In a Regulated Manner a Splice Site Choice Dominates over Selection of a Poly A Site Located in an Intron, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 26.
Conway and Wickens, Identification of Bases and Phosphates of SV40 Late Pre-mRNAs that are Required for 3'End Formation in Vitro, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 40.
Daar et al., Premature Translation Termination Mediates Mammalian mRNA Degradation, Abstract presented at meeting on RNA Processing, May 11-15, 1988, Cold Spring Harbor, p. 45.
Gallego and Nadal-Ginard, Mutually Exclusive Splicing of Myosin Light Chain (MLC) 1/3 Transcripts is Cis Regulated: Hierarchy Among Donor and Acceptor Splice Site Pairs, Abstract presented at meeting on RNA Processing, May 11-15, 1988 Cold Spring Harbor, p. 61.
Genovese and Milcarek, Alterations in Immunoglobulin mRNA Stability During B Cell Development, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 62.
Goodall et al., Specificity of Nuclear pre-RNA Splicing in Plants, Abstract presented at meeting on RNA Processing, May 11-15, 1988, Cold Spring Harbor, p. 63.
Hampson and Rottman, Alternative Processing of Bovine Growth Hormone Precursor mRNA Is Strongly Influenced by Sequences Within the Downstream Exon, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 68.
Kessler et al, A Novel Transcription Elongation Block Is Active Within the Late Leader Sequences of SV40, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 85.
Lim et al. Tissue Specificity of mRNA Degradation, Abstract presented at meeting on RNA Processing, May 11-15, 1988, Cold Spring Harbor, p. 128.
Helfman and Ricci, Studies of Alternative RNA Splicing of Tropomyosin Pre-mRNAs In Vitro, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 219.
Brady and Wold, Composition between Splicing and Polyadenylation Determines Which Adenovirus Region E3 mRNAs Are Synthesized, Abstract presented at meeting on RNA Processing May 11-15, 1988, Cold Spring Harbor, p. 224.
Marzluff and Pandey, Intervening Sequences Interfere with Formation of 3' Ends of Histone mRNAs, Abstract presented at meeting on RNA Processing, May 11-15, 1988, Cold Spring Harbor, p. 244.
Brown, J. S. W., A Catalogue of Splice Junction and Putative Branch Point Sequences from Plant Introns, Nuc. A.R. (1986) vol. 14, pp. 9549-9559.
Dedrick et al., Purified RNA Polymerase II Recognizes Specific Termination Sites during Transcription in Vitro, J. Bio. Chem. (1987) vol. 262, No. 19, pp. 9098-9108.
McDevitt et al., Requirement of a Downstream Sequence for Generation of a Poly(A) Addition Site, Cell, (1984) vol. 37, pp. 993-999.
Hanley and Schuler, Plant Intron Sequences: Evidence for Distinct Groups of Introns, Nuc. A.R. (1988) vol. 16, No. 14, pp. 7159-7176.
Gil and Proudfoot, A Sequence Downstream of AAUAAA Is Required for Rabbit .beta.-Globin mRNA 3'-End Formation, Nature (1984) bol. 312, pp. 473-474.
Sadofsky and Alwine, Sequences on the 3' Side of Hexanucleotide AAUAAA Affect Efficiency of Cleavage at the Polyadenylation Site, Mol. & Cel. Biol, (1984) vol. 4, No. 8, pp. 1460-1468.
Hofte et al. Nuc. Acids Res., vol. 15, No. 17, p. 7183, 1987.
Honigman et al., Gene, vol. 42, 1986, pp. 69-77.
Fischhoff David A.
Perlak Frederick J.
Hendricks Keith D.
Hoerner, Jr. Dennis R.
Lavin, Jr. Lawrence M.
Monsanto Company
Shear Richard H.
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