Synthetic picornavirus antigen

Details Synthetic picornavirus antigen Synthetic picornavirus antigen

1984-09-20

1988-09-06

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

530323, 530326, 530806, A61K 3900, C07K 3702

Patent

active

047692375

ABSTRACT:
A specific synthetic antigenic peptide that contains a sequence of about 20 amino acid residues corresponding to a certain region of the antigenic picornavirus capsid protein such as the VP1 capsids of foot-and-mouth disease and poliomyelitis viruses. That region is located at a distance of about 60 to about 75 percent of the total amino acid length measured from the amino-terminus. Specific synthetic peptide-containing vaccines that produce antibodies that protect animal hosts from the picornaviruses, as well as antibodies to and diagnostics for Picornavirus antigens are disclosed.

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