Synthetic phosphoglycerides possessing platelet activating prope

Details Synthetic phosphoglycerides possessing platelet activating prope Synthetic phosphoglycerides possessing platelet activating prope

1982-02-18

1985-03-12

Waltz, Thomas A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

260403, 514114, C07F 910, A61K 31685

Patent

active

045044740

ABSTRACT:
Novel synthetic glyceryl-phosphorylcholine compounds are prepared having biological activity paralleling that of naturally generated platelet activating factor.

REFERENCES:
patent: 3678137 (1972-07-01), Pfeiffer
patent: 3694473 (1972-09-01), Eibl et al.
patent: 3705213 (1972-12-01), Pfeiffer et al.
patent: 3708558 (1973-01-01), Kny
patent: 4086257 (1978-04-01), Sears
patent: 4159988 (1979-07-01), Eibl et al.
Acetyl Glyceryl Ether Phosphorylcholine: Platelet-Activating Factor, R. Neal Pinckard et al.
Chemistry and Biology of Acetyl Glyceryl Ether Phosphorylcholine (Platelet-Activating Factor), R. Neal Pinckard et al.
Hanahan, et al., Biochemistry 2:630-2:640 (1963).
Abstract TOYA*B05, 26406C/15*J5, 5028-955.
Blank et al., "Antihypertensive Activity of an Alkyl Ether Analog of Phosphatidycholine", Biochemical and Biophysical Research Communications , 90:1194-90:1200 (1979).
Demopoulos et al., J. Biol. Chem., vol. 254, No. 19, pp. 9355-9358 (10/10/1979).
Abstract TOYA*B05, 70927B/39*J5, 4106-430.

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