Synthetic peptidic substrate for determination of trypsin and .a

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

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435 7, 435 27, C07K 508

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048944386

ABSTRACT:
A synthetic peptide of the formula: ##STR1## wherein A.sub.1 is Pro or Ala, is excellent in solubility in water and substrate specificitity and is suitable as a substrate for determining trypsin and .alpha..sub.1 -antitrypsin.

REFERENCES:
patent: 3801562 (1974-04-01), Benneville
patent: 3886136 (1975-05-01), Claeson et al.
patent: 4137225 (1979-01-01), Af Ekenstam et al.
patent: 4257940 (1981-03-01), Fujii et al.
patent: 4409140 (1983-10-01), Smith et al.
patent: 4428874 (1984-01-01), Svendsen
patent: 4452736 (1984-06-01), Nagasawa et al.
patent: 4457866 (1984-07-01), Karges et al.
Chem. Abstracts, vol. 92, 1980, 159413h.
Acta Medica Scandinavica, Supp. 432, Studies in .alpha..sub.1 -antitrypsin deficiency, Eriksson, 1965, pp. 41-75.

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