Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2004-10-20
2011-10-18
Russel, Jeffrey E (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S019800, C514S021400, C514S021500, C514S021600, C514S021700, C514S021800, C530S326000, C530S327000, C530S328000, C530S329000
Reexamination Certificate
active
08039438
ABSTRACT:
Synthetic peptides derived from sucrose synthase, and having homology to actin and actin-related proteins, sharing a common motif, useful for causing acting bundling and preventing actin depolymerization. Peptides exhibiting the common motif are described, as well as specific synthetic peptides which caused bundled actin and inhibit actin depolymerization. These peptides can be useful for treating a subject suffering from a disease characterized by cells having neoplastic growth, for anti-cancer therapeutics, delivered to subjects solely, or concomitantly or sequentially with other known cancer therapeutics. These peptides can also be used for stabilizing microfilaments in living cells and inhibiting growth of cells.
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Huber Steven C
Larabell Carolyn A
Sederoff Heike
Berkeley Lawrence
Chew Wong Michelle
National Laboratory
North Carolina State University
Russel Jeffrey E
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