Synthetic peptides specific for the detection of antibodies to H

Details Synthetic peptides specific for the detection of antibodies to H Synthetic peptides specific for the detection of antibodies to H

1994-06-17

1998-05-05

Woodward, Michael P.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

530324, C12Q 170, C07K 1418

Patent

active

057472394

ABSTRACT:
The present invention relates to peptides which are immunoreactive to antibodies to HCV or NANBHV and a method of detecting the presence of HCV or NANBHV antibodies in body fluids by using the peptides as the antigen. The peptides are selected from both the envelope and non-structural protein regions of the HCV or NANBHV. The detection method includes enzyme linked immunosorbent assay or other immunoassay procedures. The peptides and conjugates or polymers thereof are also useful as immunogens in generating high titer antibodies to HCV or in vaccines.

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