Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16,

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 71, 436 64, 436813, 530321, 530325, 530326, 5303884, 5303894, C12G 170, G01N 3353

Patent

active

059324120

ABSTRACT:
The invention refer to a method for diagnosing the presence of infection of papilloma virus (PV) and of papilloma virus (PV) carrying, especially cervix cancer and condyloma, by the detection of virus specific antigen-antibody complexes in immunossay.

REFERENCES:
patent: 4748109 (1988-05-01), Baird
patent: 4777239 (1988-10-01), Schoolnik et al.
patent: 5629146 (1997-05-01), Dillner et al.
Oltersdorf et al. 1987, J. Gneral Virology, vol. 68, pp. 2933-2938.
Doorbar, Chem. Abstr., vol. 107:130591g, p. 395, Oct. 12, 1987.
Li, et al.: "Identification of the Human Papillomavirus Type Bb L1 Open Reading Frame Protein in Condylomas and Corresponding Antibodies in Human Sera"; Journal of Virology B1(9):2684-2690, 1987.
Krisch, I., et al.: "Demonstration of Secretory Component, IgA, IgG, IgM by the Peroxidase--Antiperoxidase Technique in Invested Papillomas of the Nasal Cavities"; Human Pathol. 15(10):915-20 (1984).
Medline, NLM, 86243722 Breast Cancer Res. Treat. 1986, 7(2), pp. 97-103.
Medline, NLM, 87093933 Scand. J., Dent. Res. Oct. 1986, 95(5), pp. 419-426.
Virology, vol. 175, 1990, N.D. Christensen et al.: Immunological Cross-Reactivity to Laboratory-Produced HPV-11 Virions of Polysera Raised against Bacterially Derived Fusion Proteins and Synthetic Peptides of HPV-6b and HPV-16 Capsid Proteins; see p. 1- p. 9. See in particular Table I and Discussion.
The EMBO Journal, vol. 6, No. 1, 1987, K. Seedorf et al.: Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 19) in cervical carcinoma cells. See p. 139--p. 144. See in particular fig. 3.
Int. J. Cancer, vol. 45, 1990, J. Dillner et al.: "Mapping of linear epitopes of human papillomavirus type 16: The L1 and L2 open reading frames"; See p. 529--p. 535. See table 1, peptides 39 and 49.
Proc. Natl. Acad. Sci., vol. 86, May 1989, Joakim Dillner et al.: "A synthetic peptide defines a serologic IgA response to a human papillomavirus-encoded nuclear antigen expressed in virus-carrying cervical neoplasia;" p. 3838, left column and Discussion.
Dialog Information Services, Dataase WPIL, File 351, Accession No. 5195697, TOA NENRYO KOGYO KK: Antibody formed to antigen polypeptide--contains hydrophilic part forming part of initial protein of human papilloma-virus relating to malignant diseases; Examination; JP 1061665 A 890308 8916 (Basic).
J. gen Virol., vol. 70, 1989, D. Patel et al.: Reactivities of Polyclonal and Monoclonal Antibodies Raised to the Major Capsid Protein of Human Papillomavirus Type 16; See p. 69, p. 77. See in particular Table 1 and pp. 76-77.
Dialog Information Services, Medline, File 154, Accession No. 07256206, Steele JC et al: Humoral assays of human sera to disrupted and nondisrupted epitopes of human papillomavirus type 1; Virology Feb. 1990, 174 (2), pp 388-98.
Dialog Information Services, Medline, File 154, Accession No. 06062955, Komly CA et al: "The L2 open reading frame of human papillomavirus type 1a encodes a minor structural protein carrying type-specific antigens"; J Virol (United States), Nov. 1986, 60 (2) pp. 813-6.
Dialog Information Services, Medline, File 154, Accession No. 06638652, Doorbar J. et al.: Analysis of HPV-1 E4 gene expression using epitope-defined antibodies; EMBO J, Mar. 1988, 7 (3) pp. 825-33.
J. gen. Virol., vol. 68, 1987, L. Banks, et al.: "Expression of Human Papillomavirus Type 6 and 16 Capsid Proteins in Bacteria and Their Antigenic Characterization"; See p. 3081--p. 3089. See p. 3085, last paragraph--p. 3088, last paragraph.
Virology, vol. 164, 1988, J.M. Firzlaff, et al.: "Detection of Human Papillomavirus Capsid Antigens in Various Squamous Epithelial Lesions Using Antibodies Directed against the L1 and L2 Open Reading Frames"; See p. 467--p. 477.
National Library of Medline (NLM), Database Medline, accession No. 90107938, Barbosa MS et al: "The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation"; EMBO J 1990, Jan; 9(1):153-60.
National Library of Medline (NLM), Database Medline, accession No. 90171929, Strang G., et al.: "Human T cell responses to human papillomaviurs type 16 L1 and E6 sythetic peptides: identification of T cell determinants, HLA-DR restriction and virus type specificity"; J Gen Virol 1990 Feb; 71 (Pt 2):423-31.
J. gen. Virol., vol. 67, 1986, G. Matlashewski et al.: "The Expression of Human papillomavirus Type 18, E6 Protein in Bacteria and the Production of Anti-E6 Antibodies"; See p. 1909--p. 1916.
J. gen. Virol., vol. 69, 1988, H.M. Browne et al.: "Analysis of the L1 Gene Product of Human Papillomavirus Type 16 by Expression in a Vaccinia Virus Recombinant"; See p. 1263--p. 1273.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16,, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-848596

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.