Synthetic peptides for use in tumor detection

Details Synthetic peptides for use in tumor detection Synthetic peptides for use in tumor detection

1993-05-03

1995-03-07

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 145, A61K 4902

Patent

active

053956095

ABSTRACT:
Radioactively labelled peptides comprising oligopeptides of from 3 to 10 peptide units and containing the sequence RGD and particularly the oligopeptides RGDSY and RGDFY, are disclosed as in vivo thrombus, tumor or CAM markers for the in vivo diagnosis and detection of thrombi, tumors or CAM in mammals.

REFERENCES:
patent: 4427646 (1984-01-01), Olexa et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4753875 (1988-06-01), Ryan
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 4952562 (1990-08-01), Klein et al.
patent: 4957902 (1990-09-01), Grinnell
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5053392 (1991-10-01), Klein et al.
patent: 5100875 (1992-03-01), Marguerie de Rotrou
patent: 5183804 (1993-02-01), Saiki et al.
patent: 5196510 (1993-03-01), Rodwell et al.
patent: 5262520 (1993-11-01), Plow et al.
patent: 5279812 (1994-01-01), Krstenansky et al.
patent: 5328840 (1994-07-01), Coller
Burns et al., J. Cell Biology, vol. 107, pp. 1225-1230 (Sep. 1988).
Saiki et al., Br. J. Cancer, vol. 60, pp. 722-728 (1989).
D'Souza et al., J. Biol. Chem., vol. 263, No. 8, pp. 3943-3951 (Mar. 1988).
Michael D. Pierschbacker, et al., Cell Attachment Activity of Fibronectin Can Be Duplicated By Small Synthetic Fragments of the Molecule, Nature, vol. 309, pp. 30-33, May 3, 1984.
G. E. Hanks, M.D., et al., The Outcome of Treatment of 313 Patents With T-I (UICC) Prostate Cancer Treated With External Beam Irradiation, Int'l. Radiation Onocology Biol. Phys., vol. 14, No. 2, pp. 243-248, Feb. 1988.
Marek Kloczewiak, et al., Platelet Receptor Recognition Domain On the .tau. Chain of Human Fibrinogen and Its Synthetic Peptide Analogues, Biochemistry, vol. 28, No. 7, pp. 2915-1919, 1989.
Marek Kloczewiak, et al., Platelet Receptor Recognition Site On Human Fibrinogen. Synthesis and Structure-Function Relationship of Peptides Corresponding To the Carboxy-Terminal Segment of the .tau. Chain, Biochemistry, vol. 23, pp. 1767-1774, 1984.
Jacek Hawiger, et al., Platelet Receptor Recognition Domains On The .alpha. Chain of Human Fibrinogen: Structure-Function Analysis, Biochemistry, vol. 28, pp. 2909-2914, 1989.

Affiliated with

Also associated with

Rating

Synthetic peptides for use in tumor detection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthetic peptides for use in tumor detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthetic peptides for use in tumor detection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1404639