Synthetic peptides for use in thrombus detection

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound

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530331, 424 165, A61K 5100, A61M 3614

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active

058434020

ABSTRACT:
Radioactively labelled peptides comprising oligopeptides of from 3 to 10 peptide units and containing the sequence RGD and particularly the oligopeptides RGDSY and RGDFY, are disclosed as in vivo thrombus, tumour or CAM markers for the in vivo diagnosis and detection or thrombi, tumours or CAM in mammals.

REFERENCES:
patent: 4427646 (1984-01-01), Olexa et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4753875 (1988-06-01), Ryan
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5100875 (1992-03-01), Marguerie de Rotrou
patent: 5183804 (1993-02-01), Saiki et al.
patent: 5196510 (1993-03-01), Rodwell et al.
patent: 5262520 (1993-11-01), Plow et al.
patent: 5279812 (1994-01-01), Krstenansky et al.
patent: 5328840 (1994-07-01), Coller
patent: 5395609 (1995-03-01), Stuttle
Michael D. Pierschbacker, et al., Cell Attachment Activity of Fibronectin Can Be Duplicated By Small Synthetic Fragments of the Molecule, Nature, vol. 309, pp. 30-33, May 3, 1984.
G. E. Hanks, M.D., et al., The Outcome of Treatment of 313 Patents With T-I (UICC) Prostate Cancer Treated With External Beam Irradiation, Int'l. Radiation Onocology Biol. Phys., vol. 14, No. 2, pp. 243-248, Feb. 1988.
Marek Kloczewiak, et al., Platelet Receptor Recognition Domain on the .tau. Chain of Human Fibrinogen and Its Synthetic Peptide Analogues, Biochemistry, vol. 28, No. 7, pp. 2915-1919, 1989.
Marek Kloczewiak, et al., Platelet Receptor Recognition Site On Human Fibrinogen. Synthesis and Structure-Function Relationship of Peptides Corresponding to the Carboxy-Terminal Segment of the .tau. Chain, Biochemistry, vol. 23, pp. 1767-1774, 1984.
Jacek Hawiger, et al., Platelet Receptor Recognition Domains on the .beta. Chain of Human Fibrinogen: Structure-Function Analysis, Biochemistry, vol. 28, pp. 2909-2914, 1989.
Burns et al., J. Cell Biology, vol. 107, pp. 1225-1230 (Sep. 1988).
Saiki et al., Br. J. Cancer, vol. 60, pp. 722-728 (1989).
D'Souza et al., J. Biol Chem., vol. 263, No. 8, pp. 3943-3951 (Mar. 1988).

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