Synthetic peptides for the treatment of AIDS

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence

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514 16, C07K 706, A61K 3702

Patent

active

051624990

ABSTRACT:
Synthetic linear or cyclic peptides having the formula

REFERENCES:
patent: 4737487 (1988-04-01), Watts et al.
Cantor and Schimmel, Biophysical Chemistry, Part I: The Conformation of Biological Macromolecules, W. H. Freeman and Company, pp. 42-43, 72, 110-111 and 258 (1980).
Pharmaprojects, vol. 11, Tarr (Ed.), PJB Publications Ltd pp. 1-4 (May 1990).
Rudinger, Peptide Hormone, Parsons (Ed.), U Park Press, Baltimore, 1976.
Cram et al., Organic Chemistry, 2nd ed. McGraw-Hill Book Company, New York, pp. 607-613 (1964).
C. B. Pert et al., Proc. Natl. Acad. Sci., vol. 83, pp. 9254-9258, Dec. 1986.
M. R. Ruff et al., FEBS Letters, vol. 211, No. 1, pp. 17-22, Jan. 1987.
M. R. Pincus et al., Biochem. Biophys. Res. Comm., vol. 143, No. 1, pp. 248-251, 1987.
Anthony S. Fauci, Proc. Natl. Acad. Sci., U.S.A., vol. 83, pp. 9278-9283, Dec. 1986.

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