Synthetic peptides for detoxification of bacterial endotoxins an

Details Synthetic peptides for detoxification of bacterial endotoxins an Synthetic peptides for detoxification of bacterial endotoxins an

1993-04-19

1994-10-25

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, 514 17, 530319, 530327, 530328, 530329, A61K 3702, C07K 706

Patent

active

053589335

ABSTRACT:
Novel peptides are disclosed which are based on the formula:

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Antimicrobial Agents and Chemotherapy, vol. 33, No. 9, Sep. 1989, Danner et al, "Purification, Toxicity, and Antiendotoxin Activity of Polymyxin B Nonapeptide", pp. 1428-1434.
PCT Search Report, Jun. 18, 1992, Examiner Marshall.
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Danner et al., Antimicrobial Agents and Chemotherapy, vol. 33, No. 9, pp. 1428-1434 (1989).
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Duwe et al., Antimicrobial Agents and Chemotherapy, vol. 30, No. 2, pp. 340-341 (1986).
Vaara et al., Nature, vol. 33, pp. 526-528 (1983).
Storm et al., Ann. Rev. Biochem., vol. 46, pp. 723-763 (1977).

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