Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-02-28
1999-10-26
Davenport, Avis M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 16, 424 169, 424 9, 530326, 530328, A61K 3800, A61K 3802, A61K 4900, C07K 500
Patent
active
059728906
ABSTRACT:
Vascular disease including asymptomatic atherosclerosis can be diagnosed by administering a synthetic peptide or peptide analog having an affinity for, and propensity to accumulate at, a site of vascular injury to a patient, and then detecting the location of the peptide or peptide analog within the patient's vascular system. The synthetic peptide or peptide analog may include an amino acid sequence sufficiently duplicative of the amino acid sequence of a region of either the apolipoprotein B, apolipoprotein A-I, or elastin proteins such that the peptide or peptide analog accumulates at a site of vascular injury.
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Findeis Mark A.
Fischman Allan
Lees Ann M.
Lees Robert S.
Shih Ing-Lung
Davenport Avis M.
New England Deaconess Hospital Corporation
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