Synthetic peptides corresponding to telopeptide sequences of cro

Details Synthetic peptides corresponding to telopeptide sequences of cro Synthetic peptides corresponding to telopeptide sequences of cro

1998-03-24

1999-10-05

Stucker, Jeffrey

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

6 to 7 amino acid residues in defined sequence

530328, 530356, 435 71, A61K 3804

Patent

active

059626399

ABSTRACT:
Peptides synthesized to match the human .alpha.1(I) and .alpha.2(I) telopeptide sequences of the type I collagen metabolites, preferably selected from among Asp-Glu-Lys-Ser-Thr-Gly-Gly (SEQ ID NO:5), Gln-Tyr-Asp-Gly-Lys-Gly-Val-Gly (SEQ ID NO:6), and Glu-Lys-Ala-His-Asp-Gly-Gly-Arg (SEQ ID NO:7). Useful as calibrators and antigens in immunoassays for detecting type I collagen degradation products in body fluids.

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