Synthetic peptides capable of eliciting fibrin-specific monoclon

Details Synthetic peptides capable of eliciting fibrin-specific monoclon Synthetic peptides capable of eliciting fibrin-specific monoclon

1992-08-24

1994-10-18

Lee, Lester L.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

5303879, 53038825, 530382, 43524027, A61K 3102, C07K 706, C07K 1528

Patent

active

053570421

ABSTRACT:
Peptides comprising fibrin-specific epitopic sequences are used to prepare hybridoma cell lines producing antifibrin-specific monoclonal antibodies substantially devoid of fibrinogen-cross-reactivity obtained by somatic cell fusion. The antibodies are useful for the in vivo and in vitro detection of thrombi and fibrin deposits.

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