Synthetic peptide with human interleukin 1 activity

Details Synthetic peptide with human interleukin 1 activity Synthetic peptide with human interleukin 1 activity

1986-10-20

1988-09-27

Kight, John

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

530351, 514885, C07K 706

Patent

active

047743204

ABSTRACT:
Synthetic peptide with human interleukin 1 activity, which peptide can be used as a stimulant of the immune functions and can be defined by the general formula:

REFERENCES:
March et al, Nature 315, 1985, pp. 641-645.
Lomedico et al, Nature 312, 1985, pp. 458-462.
Auron et al, PNAS 81, 1984, pp. 7907-7911.
Cameron et al, J. Exp. Med. 162, 1985, pp. 790-801.
Hopp et al, PNAS 78, 1981, pp. 3824-3825.
Dinarello et al, J. Immunol., 133, 9/1986, pp. 1332-1338.
Kack et al, J. Exp. Med., 163, 1986, pp. 463-468.
Rimsky et al, J. Immunol. 136(9) 1986, pp. 3304-3310.
Antoni et al, J. Immunol. 137(10) 1986, pp. 3201-3204.

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