Synthetic peptide targeting critical sites on the...

Details Synthetic peptide targeting critical sites on the... Synthetic peptide targeting critical sites on the...

2005-10-28

2009-02-17

Lucas, Zachariah (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S005000, C435S007100, C435S007210

Reexamination Certificate

active

07491489

ABSTRACT:
The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.

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Wong, Swee Kee et a

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