Synthetic peptide of regulatory virus protein R (VPR) of...

Details Synthetic peptide of regulatory virus protein R (VPR) of... Synthetic peptide of regulatory virus protein R (VPR) of...

2006-01-10

2006-01-10

Mosher, Mary E. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C530S324000, C530S325000, C530S326000, C530S327000, C530S402000, C530S810000

Reexamination Certificate

active

06984486

ABSTRACT:
The invention pertains to synthetic (s) peptides derived from the viral regulatory protein R (Vpr) of the human immunodeficiency virus type 1 (HIV-1), particularly the chemical synthesis of the 96 amino acid full length Vpr protein (sVpr1-96), of a 47 amino acid long N-terminal (sVpr1-47), of a 49 amino acid long C-terminal fragment (sVpr48-96) as well as fragments thereof (sVpr1-20and sVpr21-40) and further approximately 15 amino acid long fragments of sVpr1-96. As fragments or full length products of the HIV-1 regulatory protein, those products are used in biological assays, for molecular and structural characterization of Vpr and domains thereof, as well as for the development of anti-Vpr antibodies directed against Vpr peptide sequences.

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