Synthetic oligomers having chirally pure phoshonate internucleos

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 245, 536 253, C12Q 168

Patent

active

057926158

ABSTRACT:
Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.

REFERENCES:
patent: 5212295 (1993-05-01), Cook
Neckers et al., Critical Rev. Oncogenesis, 3(1,2):175-231, 1992.

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