Synthetic multiple tandem repeat mucin and mucin-like peptides,

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 723, 435 76, 435 79, 530350, G01N 3353, G01N 33574, C07K 100, C07K 1400

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058276661

ABSTRACT:
The present invention relates to novel synthetic muc-1 peptides and muc-1-like analogs including at least two 20-amino acid tandem repeats of muc-1, which synthetic muc-1 and muc-1-like peptides are capable of attaining native conformation in the absence of glycosylation. The invention also relates to methods of producing the peptides. The invention further relates to uses of the peptides, such as for vaccines and diagnostic testing.

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