Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence
Patent
1991-11-04
1993-12-21
Lee, Lester L.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
11 to 14 amino acid residues in defined sequence
530324, 530325, 530326, A61K 3702, C07K 706, C07K 708, C07K 710
Patent
active
052722520
ABSTRACT:
Synthetic pulmonary surfactants having antioxidant properties consisting of a complex of a polypeptide, with an antioxidant moiety, having an alpha-helical structure and a lipid consisting of one or more of the lipids associated with natural pulmonary surfactant were prepared. These surfactants are useful in the treatment of respiratory distress syndrome.
REFERENCES:
patent: 5134129 (1992-07-01), Lichtenberger
McLean Larry R.
Payne Marquerite H.
Lee Lester L.
Merrell Dow Pharmaceuticals Inc.
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