Synthetic Intermediates for the preparation of N, N'-Di-substitu

Details Synthetic Intermediates for the preparation of N, N'-Di-substitu Synthetic Intermediates for the preparation of N, N'-Di-substitu

1991-04-09

2000-12-12

Gupta, Yogendra N.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540356, 540523, 540529, 546243, 546245, 548473, 548517, 548518, 548530, C07D20948, C07D20509, C07D20712, C07D21136

Patent

active

061601268

ABSTRACT:
Novel Intermediates ##STR1## wherein R is a substituted or unsubstituted hydrocarbon residue or acyl group; X is an electron withdrawing group; Y.sup.1 and Y.sup.2, which are the same or different, are each independently oxygen or sulfur; and A is a substituted or unsubstituted, divalent hydrocarbon residue have potent reactivity, this being useful in preparing guanidine derivatives.

REFERENCES:
patent: 4287346 (1981-09-01), Tanaka et al.
patent: 4742060 (1988-05-01), Shiokawa et al.
patent: 4845106 (1989-07-01), Shiokawa et al.
Chupp et al, J. Org. Chem. 43(18), 3553-59 1978.
Chemical Abstracts, vol. 89 (17): 146820b (1978).
G. J. Durant et al., Cyanoguanidine--Thiourea Equivalence in the Development of the Histamine H2-Receptor Antagonist, Cimetidine, Journal of Medical Chemistry (1977), vol. 20, No. 7, 901-906.

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