Synthetic immunogen

Details Synthetic immunogen Synthetic immunogen

1988-05-06

1992-01-14

Russel, Jefrey E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 89, 424 90, 424 91, 424 92, 424450, 424460, 424468, 530322, 530330, 530403, 530404, 530405, 530406, A61K 3902, A61K 3912, A61K 3724, C07K 1700

Patent

active

050808966

ABSTRACT:
The present invention concerns novel immunogens. These immunogens comprise novel compounds which consist of an antigen or antigenic determinant couple dot an amphiphilic adjuvant molecule and optionally also free amphiphilic adjuvant molecules. An advantageous features of these novel immunogens is the presence of both an excellent immunogen activity as well as a pronounced adjuvant activity in a single complex.

REFERENCES:
patent: 4432969 (1984-02-01), Batchelor
patent: 4517304 (1985-05-01), Stott et al.
patent: 4578269 (1986-03-01), Morein
patent: 4803070 (1989-02-01), Cantrell et al.
patent: 4806350 (1989-02-01), Gerber
patent: 4806352 (1989-02-01), Cantrell
Morein et al., (1984) Nature 308:457-460.
Nourath et al., (1984) J. Gen. Virol. 65:1009-1014.
Hopp (1984) Mol. Immunol. 21:13-16.

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