Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1984-03-09
1986-07-08
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Lymphokine
424 88, 514 13, 514 14, 514 15, 514 16, 530806, 530324, 530326, 530327, 530328, A61K 3929, C07K 706, C07K 708, C07K 710
Patent
active
045992312
ABSTRACT:
Chemically synthesized polypeptides include amino acid residue sequences that substantially correspond to the amino acid residue sequences of T Cell and B cell determinant portions of a natural, pathogen-related protein, in particular, a hepatitis B virus surface antigen (HBsAG). When administered to a host alone, as polymers or as carrier-bound conjugates, the polypeptides induce the proliferation of thymus-derived cells in hosts primed against hepatitis B virus.
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Proc. Nat'l. Acad. Sci., vol. 80, 2365-69 (1983).
The Journal of Invest., 83, 112s-115s (1984).
Chisari Frank V.
Milich David R.
Phillips Delbert R.
Scripps Clinic and Research Foundation
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