Synthetic composition for storage of platelets comprising glycer

Details Synthetic composition for storage of platelets comprising glycer Synthetic composition for storage of platelets comprising glycer

1996-07-12

1998-05-19

Saucier, Sandy

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

424 9372, A01N 102

Patent

active

057534284

ABSTRACT:
The platelet preservation solution does not containing any plasma proteins but includes 5 to 100 mM of glycerol, from 5 to 15 mM of sodium citrate, from 10 to 30 mM of sodium acetate, from 10 to 50 mM of disodium hydrogen phosphate, up to 10 mM of citric acid, up to 50 mM of glucose and from 50 to 150 mM of electrolyte compounds in addition to the sodium acetate, disodium hydrogen phosphate and sodium citrate. The electrolyte compounds include sodium chloride. The artificial platelet preservation solution prevents adverse reactions caused by plasma components resulting in a greater platelet survival ratio during storage.

REFERENCES:
patent: 4992363 (1991-02-01), Murphy
patent: 5376524 (1994-12-01), Murphy et al.

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