Synthetic catalytic oligonucleotide structures

Details Synthetic catalytic oligonucleotide structures Synthetic catalytic oligonucleotide structures

1992-06-22

1994-08-02

Stone, Jacqueline

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 243, 536 253, 424 2, 935 3, C07H 1700, C07H 2300, A01N 4304, A61K 3170

Patent

active

053347110

ABSTRACT:
A synthetic catalytic oligonucleotide structure and nucleotides having the general structural formula (I) contains: ##STR1## in which B represents a nucleoside base which is in particular selected from the group comprising adenin-9-yl (A), cytosin-1-yl (C), guanin-9-yl (G), uracil-1-yl (U), uracil-5-yl (.psi.), hypoxanthin-9-yl (I), thymin-1-yl (T) and 2-aminoadenin-9-yl,

REFERENCES:
patent: 4469863 (1984-09-01), Ts'o et al.
J-P Perreault et al. (1990) Nature 344: 565-567.
Iribarren et al, Proceedings of the National Academy of Sciences of USA, Oligoribonucleotides as Antisense Probes., vol. 87, No. 19, Oct. 1990.
Hampel et al, Biochemistry, RNA Catalytic Properties of the Minimum (-)s TRSV Sequence, vol. 28, No. 12, Jun. 13, 1989.
Sproat et al, Nucleic Acids Research, New Synthetic Routes to Synthons Suitable for 2'-0-allyloligoribonucleotide Assembly., vol. 19, No. 4, 1991.
Sproat et al, Nucleic Acids Research, New Synthetic Routes to Protected Purine 2'-O-Methylriboside-3'-O-Phosphoramidites Using a Novel Alkylation Procedure., vol. 18, No. 1, 1990.
Hampel et al, Nucleic Acids Research, Catalytic RNA Model: Evidence for Helices and Sequence Requirement for Substrate RNA., vol. 18, No. 2, 1990.
Hutchins et al, Nucleic Acids Research, Self-Cleavage of Plus and Minus RNA Transcripts of Avocado Sunblotch Viroid, vol. 14, No. 9, 1986.

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