Synthetic bulk laxative

Details Synthetic bulk laxative Synthetic bulk laxative

2005-11-29

2005-11-29

Venkat, Jyothsna (Department: 1615)

Drug, bio-affecting and body treating compositions

Digestive system regulator containing solid synthetic...

C424S435000, C424S451000, C424S464000

Reexamination Certificate

active

06969511

ABSTRACT:
A synthetic bulk laxative which comprises a crosslinked graft polymer. It is formed of a hydrophilic monomer partially neutralized up to 75%, a polysaccharide gum up to 3% by weight and a crosslinker up to 2% by weight. The weight percentages are with respect to the hydrophilic monomer. A process for the preparation of the synthetic bulk laxative which comprises up to 75% partial neutralization of a hydrophilic monomer with an alkali. The partially neutralized hydrophilic monomer is polymerized with up to 2% by weight of a cross linker and up to 3% by weight of a polysaccharide gum in the presence of an initiator in an organic solvent under inert atmosphere at 30–80° C. The synthetic bulk laxative is dried at 30–120° C. and pulverized. A formulation of the synthetic bulk laxative in combination with pharmaceutically acceptable excipients.

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