Synthetic bone matrix

Details Synthetic bone matrix Synthetic bone matrix

1995-05-18

2000-06-20

Isabella, David J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

A61F 228

Patent

active

060779888

ABSTRACT:
Disclosed is an osteogenic device capable of inducing the formation of endochondral bone in a shape conforming substantially to the shape of the device when implanted in a mammalian host. The device includes an osteogenic protein dispersed within a porous matrix comprising a polymer of collagen and glycosaminoglycan cross-linked to an M.sub.c value of about 800 to about 60,000. Also disclosed are a method of inducing mammalian bone growth, and a method of inducing conductive bone growth from viable mammalian bone.

REFERENCES:
patent: 4418691 (1983-12-01), Yannas et al.
patent: 4947840 (1990-08-01), Yannas et al.
patent: 5007934 (1991-04-01), Stone
patent: 5258043 (1993-11-01), Stone
patent: 5266683 (1993-11-01), Oppermann et al.

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