Synthetic arginine substituted peptides and their use

Details Synthetic arginine substituted peptides and their use Synthetic arginine substituted peptides and their use

2011-04-19

2011-04-19

Kemmerer, Elizabeth C. (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

C530S326000, C530S345000, C514S001100, C514S002400, C514S002500

Reexamination Certificate

active

07928185

ABSTRACT:
The present invention relates to new arginine substituted peptides designed based on the sequence of human lactoferrin and to use thereof, in particular for treatment and/or prevention of infections, inflammations, tumours, pain, wounds and/or scars.

REFERENCES:
patent: 07-145196 (1995-06-01), None
patent: 07-274970 (1995-10-01), None
patent: 08-040925 (1996-02-01), None
patent: 08-143468 (1996-06-01), None
patent: WO01/34641 (2001-05-01), None
Chapple et al., Infect. Immun., 1998, vol. 66(6):2434-2440.
Odell et al., FEBS Lett., 1996, vol. 382(1-2):175-178.
Bellamy et al., Biochim. Biophys. Acta, 1992, vol. 1121(1-2):130-136.
European Patent Office Communication dated Apr. 17, 2008.
Odell, E.W. et al.: “Antibacterial Activity of Peptides Homologous to a Loop Region in Human Lactoferrin”, Febs Letters, Elsevier, Amsterdam, NL, vol. 382, 1996, pp. 175-178.
Van Berkel, P.H.C. et al.: “N-Terminal Stretch ARG2, ARG3, ARG4 and ARG5 of Human Lactoferrin Is Essential for Binding to Heparin, Bacterial Lipopolysaccharide, Human Lysozyme and DNA”, Biochemical Journal, Portland Press, London, GB, vol. 328, Nov. 15, 1997, pp. 145-151.
Azuma, M. et al.: “Antibacterial activity of multiple antigen peptides homologous to a loop region in human lactoferrin”, Journal of Peptide Research, vol. 54, No. 3, Sep. 1999, pp. 237-241.
Moriarty, L.C. et al.: “Factors contributing to the potency of antimicrobial cationic peptides from the N-terminal region of human lactoferrin”, FEMS Microbiology Letters, Amsterdam, ML, vol. 239, No. 2, Oct. 15, 2004, pp. 295-299.
Lönnerdal, B.: “Lactoferrin Receptors in Intestinal Brush Border Membranes,” Lactoferrin: Structure and Function, ed. T.W. Hutchens et al., Plenum Press, Nyew Yor, 1994, pp. 171-175.
Bellamy, W. et al.: “Identification of the bactericidal domain of lactoferrin,” Biochimica et Biophysica Acta, 1121 (1992), pp. 130-136, Elsevier Science Publishers B.V.
Bellamy, W. et al.: “Antibacterial spectrum of lactoferrin B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin,” J. Applied Bacteriology 1992, 73, pp. 472-479.

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