Synthetic antisense oligodeoxynucleotides targeted to AChE

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology

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435 6, 435 911, 435325, 435354, 435455, 536 231, 536 2431, 536 2433, 536 245, 514 44, C07H 2104, C12Q 168, C12N 1500, A61K 4800

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061107425

ABSTRACT:
A synthetic nuclease resistant antisense oligodeoxynucleotide (AS-OND) capable of selectively modulating human acetylcholinesterase production in the central nervous system is provided. In an embodiment the antisense oligodeoxynucleotide can be selected from

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