Synthetic antigenically-active polypeptide and a process for its

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424177, 424 88, 2601125R, 23230B, 252408, A61K 3900, A61K 3700, C07C10352, C01N 3100

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active

043270751

ABSTRACT:
A synthetic antigenically active polypeptide, which includes the amino acid sequence:H-Asp-Ala-Glu-Gln-Arg-Gly-Glu-Leu-Ala-Ile-Arg-Asp-Ala-Asn-Ala-Arg -Leu-Ser-Glu-Leu-OH; a process for the preparation of such polypeptide; an antigenic agent comprising such polypeptide convalently bonded to an immunogenically active carrier; a pharmaceutical composition comprising such polypeptide or antigenic agent together with a pharmaceutically acceptable carrier or diluent; and a method for determining the presence or absence in a biological sample of antibodies monospecific to such polypeptide, which comprises introducing into the sample such polypeptide or such agent or such composition and determining the presence or absence of agglutination.

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patent: 3960827 (1976-06-01), Bjorklund
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patent: 4033940 (1977-07-01), Hughes et al.
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patent: 4160018 (1979-07-01), Bjorklund
patent: 4160019 (1979-07-01), Bjorklund
patent: 4174385 (1979-11-01), Reid
Luning et al., Chem. Abstrs., vol. 87, 1977, 165843m, 116227e, 82872u.

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