Synthetic antigenic peptide derived from hepatitis B surface ant

Details Synthetic antigenic peptide derived from hepatitis B surface ant Synthetic antigenic peptide derived from hepatitis B surface ant

1983-05-12

1986-03-25

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

045782172

ABSTRACT:
There is disclosed a new synthetic peptide which evokes an immunological response. The synthetic peptide, moreover, interacts with antibodies to hepatitis B surface antigen (HBsAg). Thus, the synthetic peptide is useful as an immunizing agent in a vaccine as an active component thereof where it serves to produce antibodies in vivo which are protective against hepatitis B virus. The synthetic peptide of the invention comprises the following sequence of amino acids: Arg Trp Met Met Leu Arg Arg (I) and preferably has the following sequence: Gly Tyr Arg Trp Met Met Leu Arg Arg Phe Gly (II).

REFERENCES:
patent: 4493795 (1985-01-01), Nestor, Jr. et al.
patent: 4493796 (1985-01-01), Rinehart, Jr.
patent: 4496521 (1985-01-01), Lewis
patent: 4499080 (1985-02-01), Duflot et al.
patent: 4499081 (1985-02-01), Laerum
Journal of Medical Virology, 11, 115-124 (1983).
Journal of Virological Methods, 3, 349-354 (1982).
Journal of Virological Methods, 4, 177-185 (1982).
Intervirology, 16, 176-183 (1981).
Proceedings of the National Academy of Sciences, 79, No. 13 (1982) pp. 4400-4404.
Molecular Immunology, 18, No. 9, pp. 869-872 (1981).
C. R. Acad. Sc. Paris, 292, 26 Jan. (1981) 373-8.
Proceedings of the National Academy of Sciences, (1981) 78, 3824-3828.
Molecular Immunology, 18, 237-244 (1981).

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