Synthetic antigen for the detection of AIDS-related disease

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 79, 435 792, 435974, 530324, 530826, 930221, 930DIG821, G01N 33569, C07K 710

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050752111

ABSTRACT:
Novel peptides are provided having substantially the same sequence as immunologically significant fragments of AIDS-related viruses. The polypeptides can be used as reagents in the determination of exposure of a human host to the virus. Of particular interest is the use of polypeptides in screening blood products.

REFERENCES:
patent: 4629783 (1986-12-01), Cosand
patent: 4661445 (1987-04-01), Saxinger et al.
patent: 4704357 (1987-11-01), Mitsuya et al.
patent: 4708818 (1987-11-01), Montagnier et al.
patent: 4716102 (1987-12-01), Levy
patent: 4833072 (1989-05-01), Krchnak et al.
Chanh et al., "Induction of anti-HIV neutralizing antibodies by synthetic peptides" EMBO Journal, 5(11) 3065-3071, 1986.
Steimer et al., "Recombinant Polypeptide from the Endonuclease Region of the Acquired Immune Deficiency Syndrome Retrovirus Polymerase (pol) Gene Detects Serum Antibodies in Most Infected Individuals" Journal of Virology, 5B(1) 9-16, 1986.
Kennedy et al., "Antiserum to a Synthetic Peptide Recognizes the HTLV-III Envelope Glycoprotein" Science, 231 1556-59, 3/28/86.
Chanh et al., "Human immunodeficiency virus gp120 glycoprotein detected by a monoclonal antibody to a synthetic peptide" Eur. J. Immunology 16: 1465-1468 (1986).
Arya et al., "Three novel genes of human T-lymphotropic virus type III: Immune reactivity of their products with sera from acquired immune deficiency syndrome patients" Proc. Natl. Acad. Sci. USA, 83: 2209-2212 Apr. 1988.
Allan et al., "Major Glycoprotein Antigens That Induce Antibodies in AIDS Patients are Encoded by HTLV-III" Science 228:1091-1094, 5/31/85.
Crowl et al., "HTLV-III env Gene Products Synthesized in E. coli Are Recognized by Antibodies Present in the Sera of AIDS Patients" Cell 41:979-986, Jul., 1985.
Ortho Diagnostic Systems, "Synthetic peptides for human T cell leukemia virus test", Chemical Abstracts 105 (1986) abstract #173060j.
Wang et al., "Detection of antibodies to human T-lymphotropic virus type III by using a synthetic peptide of 21 amino acid residues corresponding to a highly antigenic segment of gp41 envelope protein", Proc. Natl. Acad. Sci. USA 83:6159-6163, Aug. 1986.

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