Synthetic antibody mimics--multiple peptide loops attached to a

Details Synthetic antibody mimics--multiple peptide loops attached to a Synthetic antibody mimics--multiple peptide loops attached to a

1996-09-13

1998-06-23

Green, Lora M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436501, 530300, 530317, 530345, G01N 3353, C07K 502

Patent

active

057703809

ABSTRACT:
A synthetic antibody mimic comprising multiple peptide loops built on an organic or molecular scaffold. In a highly preferred embodiment of the invention, a calixarene unit comprises the organic scaffold to which is attached a plurality of peptide loops. The antibody mimics allow for the generation of large libraries of artificial antibodies that can be screened for binding to target antigens.

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