Chemical apparatus and process disinfecting – deodorizing – preser – Chemical reactor – Organic polymerization
Patent
1992-07-06
1995-05-30
Warden, Robert J.
Chemical apparatus and process disinfecting, deodorizing, preser
Chemical reactor
Organic polymerization
422131, 422102, 935 88, C08F 800
Patent
active
054198747
ABSTRACT:
The present invention is directed to a synthesis reaction column which can be conveniently implemented in post synthesis procedures. The reaction column is configured to allow easy connection to a syringe and post synthesis reagent container without requiring connection adapters.
In one embodiment, the reaction column configured in the form of a cylindrical column containing the solid-phase support and having a narrow bore tube extending at one end. The tube functions as a piercing tip for accessing a septum sealed vial containing post synthesis reagent. In another embodiment, the reaction column is configured in the form of a cylindrical barrel enclosing the solid-phase support and having a threaded mount at one end. To complement the reaction column for post synthesis procedures, a vial having a complementary threaded mount at the opening is used for containing a reagent. This vial is conveniently threaded onto the end of the barrel without adapters. Consequently, post synthesis procedures can be implemented conveniently. Both embodiments may be conveniently connected to the reagent delivery system in an automated instrument for carrying out synthesis procedures, as well as post synthesis procedures.
REFERENCES:
patent: 3886928 (1975-06-01), Sarstedt
patent: 4810471 (1989-03-01), Wachob et al.
patent: 4892710 (1990-01-01), Wong et al.
patent: 4927605 (1990-05-01), Dorn et al.
patent: 5057426 (1991-10-01), Henco et al.
patent: 5061635 (1991-10-01), Shively
patent: 5093079 (1992-03-01), Bakaitis et al.
patent: 5137695 (1992-08-01), Rusnak et al.
patent: 5152965 (1992-10-01), Fisk et al.
patent: 5179024 (1993-01-01), Dahms
patent: 5186898 (1993-02-01), Bridgham et al.
patent: 5219529 (1993-06-01), Ngo et al.
patent: 5252296 (1993-10-01), Zuckermann et al.
McMaster-Carr 1991 catalog (2 pages).
Applied Biosystems Inc. Model 391 PCR-Mate EP DNA Synthesizer Customer Installation Guide (5/89).
Pharmacia Gene Assembler.RTM. Plus Owners Manual (1991).
MilliGen/Biosearch Cyclone.TM. Plus DNA Synthesizer Operator's Manual (1989).
American Biotech Lab article, "A Simple Manual Method for Oligonucleotide Sythesis" by M. E. Schott. pages 20-23 (1985).
Coassin Peter J.
Hanna Edward G.
Mc Kinney Carlton B.
Rampal Jang B.
Sasaki Glenn C.
Beckman Instruments Inc.
Harder Paul R.
May William H.
Schneck Thomas
Snider Theresa T.
LandOfFree
Synthesis reaction column does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Synthesis reaction column, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis reaction column will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-359765