Synthesis process for 2-(3-hydroxy-1-adamantyl)-2-oxoacetic...

Organic compounds -- part of the class 532-570 series – Organic compounds – Percarboxylic acids or salts thereof

Reexamination Certificate

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C562S409000, C562S418000, C562S427000, C514S010100

Reexamination Certificate

active

11228055

ABSTRACT:
A highly advantageous process for the preparation of 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid or a salt thereof is described. The process comprises subjecting 1-acetyl 3-hydroxyadamantane to liquid phase oxidation with permanganate to produce 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid or a salt thereof, with acidification to form the free acid when appropriate.

REFERENCES:
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patent: WO 2004/052850 (2004-06-01), None
patent: WO 2004052850 (2004-06-01), None
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