Synthesis of vicinal diamines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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522100, 564321, 564370, 564372, 564472, 564489, C07C20962

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active

051050145

ABSTRACT:
The present invention relates to an improved method of forming vicinal diamines. The method according to the present invention has the advantage of being highly stereoselective, capable of forming a wide variety of diamines including racemic and enantiomeric forms, and employing readily available starting and reaction materials.
In particular the present invention relates to a method of forming vicinal diamines from a bis-imine precursor using nucleophilic additions of organometallic reagents.

REFERENCES:
patent: 4792631 (1988-12-01), Mueller et al.

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