Synthesis of trifluoromethyl-substituted compounds

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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204169, 250542, 260429R, 2604291, 2604297, 260448A, 260607R, B01K 100, C07F 500, C07F 700, C07F 1700

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039545857

ABSTRACT:
Trifluoromethyl-substituted compounds are formed in a corona discharge or glow discharge plasma of trifluoromethyl radicals from an organic trifluoromethyl source. A substrate possessing easily replaceable ligands such as halogen or carbonyl, is initially contacted either in the plasma and within a short distance from a downstream visible edge of the plasma or outside of the visible portion of the plasma and within a short distance from the downstream visible edge, to effect a substitution of the halogen or carbonyl ligand on the substrate with a trifluoromethyl radical without substantial decomposition of the substrate.

REFERENCES:
patent: 3068510 (1962-12-01), Coleman
patent: 3081245 (1963-03-01), Farlow
patent: 3240691 (1966-03-01), Mastrangelo
patent: 3317618 (1967-05-01), Haszeldine
patent: 3397132 (1968-08-01), Wolinski
patent: 3674667 (1972-04-01), Manion
Advances in Organometallic Chemistry, Vol. 1, p. 165, by Stone et al., Pub. by Academic Press, N.Y., 1964.
Jacob et al., Jr. Chem. Soc. Chem. Comm., 1973 (4), pp. 104 and 105, Pub. Feb. 21, 1973.

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