Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydr

Details Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydr Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydr

1982-03-29

1983-11-08

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239A, 424274, C07D48704

Patent

active

044141556

ABSTRACT:
Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: ##STR1## wherein R.sup.3 is a readily removable carboxyl protecting group.

REFERENCES:
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patent: 4273709 (1981-06-01), Christensen et al.
patent: 4282148 (1981-08-01), Liu et al.
patent: 4287123 (1981-09-01), Liu et al.
patent: 4312871 (1982-01-01), Christensen et al.
patent: 4318912 (1982-03-01), Christensen et al.
patent: 4344885 (1982-08-01), Liu et al.
patent: 4349687 (1982-09-01), Liu et al.
patent: 4350631 (1982-09-01), Christensen et al.

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