Synthesis of tetrahydro-2-furylated pyrimidine derivatives

Details Synthesis of tetrahydro-2-furylated pyrimidine derivatives Synthesis of tetrahydro-2-furylated pyrimidine derivatives

1990-10-12

1991-12-24

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544317, 544318, C07D40704

Patent

active

050754467

ABSTRACT:
The synthesis of 1-(tetrahydro-2-furyl) pyrimidine derivatives in good yields by the reaction of trimethylsilylated pyrimidine bases with 2-acetoxytetrahydrofuran using a catalytic amount of cesium chloride in acetonitrile under mild conditions is described.

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