Synthesis of steroids

Details Synthesis of steroids Synthesis of steroids

1981-08-10

1982-10-19

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955C, 2603971, 2603973, C07J 7100

Patent

active

043549721

ABSTRACT:
This invention relates to the synthesis of steroids which are useful for their biological activity or which may be converted to steroids which have such activity. These syntheses include the steroid compounds and processes for their preparation.
An object of the invention is to provide syntheses which are applicable to materials which are readily available in good supply for converting such materials to steroids which are useful and desirable in the manufacture of pharmaceutical products.
More particularly, I have sought to discover processes and intermediate compounds useful in the synthesis of 24, 25-dihydroxycholesterol from hyodeoxycholic acid or lithocholic acid which are constituents of, and readily available from, animal bile.

REFERENCES:
patent: 4174345 (1979-11-01), Kaiser
patent: 4217279 (1980-08-01), Kaiser

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