Synthesis of steganacin and derivatives thereof

Details Synthesis of steganacin and derivatives thereof Synthesis of steganacin and derivatives thereof

1976-08-18

1977-11-22

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D31744

Patent

active

040595935

ABSTRACT:
Steganacin and Steganangin, dibenzocyclooctadiene lignan lactones, have been reported to possess anti-leukemic activity. This invention describes the first total synthesis of these compounds and other relevant intermediates.

REFERENCES:
becker et al., J. Chem. Soc., Chem. Commun., pp. 430-431 (1974).
Hughes et al., Tetrahedron Letters, No. 18, pp. 1543-1546 (May, 1976).
Kende et al., J. Am. Chem. Soc. 98, pp. 267-268 (1976).

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