Synthesis of renin inhibitors involving a cycloaddition...

Details Synthesis of renin inhibitors involving a cycloaddition... Synthesis of renin inhibitors involving a cycloaddition...

2011-07-05

2011-07-05

Anderson, Rebecca L (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07973175

ABSTRACT:
The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III,wherein R, R1, and R′ are as defined in the specification, or a salt thereof, and a compound of formula IVwherein R, R1, R2and R′ are as defined in the specification, and processes of manufacturing these.

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