Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

Details Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

1974-11-08

1976-08-03

Raymond, Richard L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260534R, C07C 9900, C07C10110

Patent

active

039729214

ABSTRACT:
The racemates of 2-deutero-3-fluoro-alanine and its salts are prepared by reductive amination of 3-fluoro-pyruvic acid, its hydrate or salts thereof, via the intermediate 2-imino-3-fluoro propionic acid salt, using alkali metal borodeuterides as reducing agents. The racemates thus obtained are valuable in the production of the corresponding 2-deutero-3-fluoro-D-alanine, and its pharmacologically acceptable salts, and derivatives thereof, which are potent antibacterial agents.

REFERENCES:
patent: 2610212 (1952-09-01), Floyd
patent: 2839547 (1958-06-01), Berther
Greenstein et al., Chemistry of the Amino Acids, vol. 3, John Wiley & Sons, Inc., New York, 1961, pp. 1829 and 1830.

Affiliated with

Also associated with

Rating

Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1929063