Synthesis of quinic acid from glucose

Details Synthesis of quinic acid from glucose Synthesis of quinic acid from glucose

1992-09-30

1998-08-25

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435 691, 435132, 4351723, 43525231, 43525233, 435232, 4353201, 435133, 536 231, 536 232, C12P 740

Patent

active

057982368

ABSTRACT:
There are described methods for the synthesis of quinoid organic compounds from a renewable energy source such as glucose. The method comprises enhancing the amount of glucose equivalents introduced into the pathway, blocking the common pathway so as to accumulate dehydroquinate and converting the dehydroquinate to quinic acid.

REFERENCES:
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Doctoral Dissertation of Karen Draths (1991) Microbial Biocatalysis: Syntesis of Aromatics from D-glucose Davis et al; Meth. Enzymol.; 1995; 2:300.
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Chemical Abstract, vol. 93, No. 25, 22 Dec. 1980, US Abstract No. 235226n.
K.M. Draths, et al., JACS, vol. 144, No. 24, 18 Nov. 1992, pp. 9725-9726.
Catalogue of Borterin & Borteriphege 17th Edit 1989 p. 111.
Schweizer et al. "Cloning the Guinic Acid (GA) Gene . . . " Gene 14:23-32 1981.
Pongor, S. 1987. Method in Enyznology 154:450-473.

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