Synthesis of pyridooxazinyl-indoles

Details Synthesis of pyridooxazinyl-indoles Synthesis of pyridooxazinyl-indoles

1993-10-20

1996-05-21

Datlow, Philip I.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C07D49804

Patent

active

055191312

ABSTRACT:
This application relates to a process for the preparation of indolylpyridooxazines of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification which comprises cyclizing compound of the formula ##STR2## in the presence of a strong base such as sodium hydride or potassium t-butoxide.

REFERENCES:
patent: 4029657 (1977-06-01), Dietsche
Matsuo et al., Chemical Abstract vol. 89, No. 6335x (1978), for JP 78-02, 498 (1978).
March, Advanced Organic Chemistry, 2d ed. (1977), p. 331.

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