Synthesis of platinum (IV) antineoplastic agents

Details Synthesis of platinum (IV) antineoplastic agents Synthesis of platinum (IV) antineoplastic agents

1984-04-12

1985-10-29

Sneed, Helen M. S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C07F 1500

Patent

active

045501874

ABSTRACT:
There is provided a method of synthesizing tetrachlorocyclohexanediammine platinum (IV) compounds in high purity and yield, the level of purity being suitable for pharmacological use. The compounds produced by this process have antineoplastic agents against tumor cells resistant to cis-platinum.

REFERENCES:
patent: 4431666 (1984-02-01), Bulten et al.
patent: 4466924 (1984-08-01), Verbuk et al.
patent: 4482569 (1984-11-01), Bulten et al.

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