Chemistry of carbon compounds – Miscellaneous organic carbon compounds
Patent
1975-08-11
1977-10-25
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
2601125R, C08L 8900, C07C10352
Patent
active
040555240
ABSTRACT:
Resin peptides useful in the preparation of peptides having biological activity, and particularly such resin peptides containing R-CH.sub.2 -Phe-Glu at one end of an amino acid chain, R being the resin and Phe and Glu being the residues of the amino acids phenylalanine and glutamic acid; and processes for the preparation of such resin peptides. Resin peptides are disclosed which contain amino acid chains identical with the amino acid chains of natural peptides having biological activity. Other resin peptides are disclosed which contain amino acid chains in which the amino acid residues differ in kind and sequence from amino acid chains of natural biologically active peptides but from which peptides having biological activity may be derived.
REFERENCES:
schroder, E. and K. Lubke, "The Peptides", vol. 1, Academic Press, New York, 1965, pp. 77-97.
J. M. Stewart and J. D. Young, "Solid Phase Peptide Synthesis," Freeman and Co., San Francisco, 1969, pp. 13-20.
Bossinger Charles D.
Colescott Robert L.
Cook Paul I.
Kaiser Emil
Armour Pharmaceutical Company
Barber Frank T.
Batz Carl C.
Mybeck Richard R.
Phillips Delbert R.
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