Synthesis of peptides

Details Synthesis of peptides Synthesis of peptides

1976-02-13

1980-12-30

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

2601125R, 424177, C08L 3700, C07C10352, A61K 3700

Patent

active

042422388

ABSTRACT:
Resin peptides useful in preparing peptides having biological activity, and particularly such resin peptides containing ALA-GLU-CH.sub.2 - R at one end of an amino acid chain, R being the resin and ALA and GLU being the residues of the amino acids alanine and glutamic acid; and processes for the preparation of such resin peptides. Resin peptides including ACTH.sup.1-28 are disclosed which have adrenocorticotropic activity along with processes for their preparation.

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patent: 3917579 (1975-11-01), Bumpus et al.
patent: 3926938 (1975-12-01), Hughes et al.
patent: 3987014 (1976-10-01), Guiducci et al.
patent: 3988307 (1976-10-01), Gross
patent: 4002740 (1977-01-01), Goldstein et al.
patent: 4022760 (1977-05-01), Tinney
Bajusz et al., Chem. Abstr. 71:77857h (1969).
Laslo et al., Chem. Abstr. 75:905x (1971).
Pekkarinen et al., Chem. Abstr. 70:538b (1969).
Bruckner et al., Chem. Abstr., 72:3777f (1970).
J. M. Stewart and J. D. Young, "Solid Phase Peptide Synthesis", Freeman and Co., San Francisco, 1969, pp. 1-5, 19, 20.

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