Synthesis of oxindoles from anilines and intermediates therein

Details Synthesis of oxindoles from anilines and intermediates therein Synthesis of oxindoles from anilines and intermediates therein

1977-05-02

1979-01-16

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260558S, 560 16, C07D20934

Patent

active

RE0298824

ABSTRACT:
Preparing oxindoles and intermediates therefor by reacting an N-haloaniline with .beta.-thio ester or .beta.-thio amides to form an azasulfonium halide, reacting the azasulfonium halide with a base to form an ortho[thio-ether (hydrocarbonoxycarbonyl) alkyl]aniline, or a [thio-ether (aminocarbonyl) alkyl]aniline, reacting the ortho-substituted aniline with an acid to form a 3-thio-ether-2-oxindole, and then reducing the 3-thio-ether-2-oxindole with Raney Nickel to form the 2-oxindole.

REFERENCES:
patent: 3189617 (1965-06-01), Archer et al.
patent: 3972894 (1976-08-01), Gassman
Gassman et al., J. Am. Chem. Soc., vol. 95, pp. 2718-2719, (Apr. 18, 1973).

Affiliated with

Also associated with

Rating

Synthesis of oxindoles from anilines and intermediates therein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of oxindoles from anilines and intermediates therein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of oxindoles from anilines and intermediates therein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-645908